Blood Ties follows the misadventures of Vicki Nelson (Christina Cox), a feisty, attractive, 29-year old ex-cop turned private investigator, who seems destined to sit on the sidelines until fate intervenes, turning her life upside down. After witnessing a terrifying murder, she finds herself on a collision course with a stranger who is also investigating the case. He is Henry Fitzroy (Kyle Schmid), a 450-year old vampire who just happens to be the bastard son of King Henry VIII. After solving the murder, Vicki finds her forays into supernatural crime are anything but over. Week after week, Vicki's relationship with Henry draws her into baffling cases involving a terrifying pantheon of occult adversaries. Forget fraud investigations and cheating spouses - she's squaring off against ghosts, goblins and ghouls. Vicki and Henry's unlikely alliance soon progresses beyond a purely professional arrangement, complicating her relationship with her long-suffering ex-partner in policing and love, Detective Mike Celluci (Dylan Neal) and pretty well everything else in her life.